Liver function Test (LFT)

The Liver Function Test (LFT) is a comprehensive assessment of liver health, analyzing markers such as bilirubin, liver enzymes (SGPT and SGOT), and proteins like albumin and globulin. This test helps detect liver inflammation, cell damage, bile duct issues, and protein production efficiency, making it crucial for overall liver health management.

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Description

 Tests included : 

✔️Bilirubin Total: Measures the total amount of bilirubin, a byproduct of red blood cell breakdown. Elevated levels may indicate liver or bile duct issues.

✔️Bilirubin Direct: Assesses direct (conjugated) bilirubin, which is processed by the liver. High levels can suggest liver dysfunction or bile duct obstruction.

✔️Bilirubin Indirect: Evaluates indirect (unconjugated) bilirubin, produced before liver processing. High levels may point to excessive red blood cell breakdown or liver issues.

✔️Alkaline Phosphatase (ALP): Enzyme test that indicates bile duct health and may also reveal liver or bone disorders if elevated.

✔️SGPT (ALT): Measures the enzyme alanine transaminase, primarily found in the liver. Elevated ALT levels can be a sign of liver cell damage.

✔️SGOT (AST): Measures aspartate transaminase enzyme levels, present in both liver and muscle tissue. High AST can signal liver or muscle-related damage.

✔️Total Protein: Reflects the combined levels of proteins, albumin, and globulin. Total protein levels help assess liver health and nutritional status.

✔️Globulin: A group of proteins involved in immune response and blood clotting. Abnormal levels may indicate liver or immune issues.

✔️Serum Albumin: Measures albumin, a protein made by the liver, which helps maintain fluid balance. Low levels can indicate chronic liver disease or malnutrition.

The Liver Function Test (LFT) measures a range of enzymes, proteins, and bilirubin levels in the blood to provide a thorough assessment of liver health. By examining markers like SGPT, SGOT, bilirubin, and albumin, LFT helps detect liver inflammation, bile duct obstructions, and damage to liver cells. Regular LFTs are essential for monitoring liver function, especially for those with liver-related symptoms, chronic liver disease, or on liver-impacting medications.

  • Bilirubin (Total, Direct, Indirect): Indicates liver’s ability to process and eliminate bilirubin, assessing red blood cell breakdown and bile duct health.
  • Alkaline Phosphatase (ALP): Evaluates bile duct health and may reveal liver or bone conditions.
  • SGPT (ALT) and SGOT (AST): Liver enzymes that indicate liver cell health; elevated levels suggest liver cell injury.
  • Total Protein & Globulin: Assesses the protein synthesis capacity of the liver and immune response.
  • Serum Albumin: Checks for liver’s ability to produce albumin, vital for fluid balance and overall liver function.
  • Fasting: It is generally advised to fast for 8-12 hours before the test to get accurate results.
  • Hydration: Drink water to stay hydrated but avoid other beverages before the test.
  • Medication Disclosure: Inform your healthcare provider about any medications or supplements, as certain drugs may influence liver enzyme levels.
 

FAQ'S

What does the Liver Function Test (LFT) detect?

LFT checks various enzymes, proteins, and bilirubin levels in the blood to evaluate liver health. It can reveal inflammation, liver cell damage, bile duct issues, and more, helping diagnose liver-related conditions early.

Do I need to fast before taking the LFT?

Yes, fasting for 8-12 hours is generally recommended before the test to ensure accurate results. Drinking water is fine, but other beverages and food should be avoided.

How often should I get an LFT done?

Regular LFTs are advised if you have liver disease, take medications that affect the liver, or experience symptoms like jaundice or fatigue. Your doctor can provide guidance based on your specific health needs.

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